Study | Study Design | Number of Patients | Surgery Type | Outcomes | Findings |
---|---|---|---|---|---|
Pfister et al, 201022 | Randomized, controlled | 58 | Neck dissection | Postoperative pain and dysfunction | Reduction in postoperative pain and dysfunction compared to usual care (P = 0.008) |
Sahmeddini et al, 201025 | Randomized, controlled | 90 | Nasal septoplasty | Postoperative pain | Similar analgesic effect as meperidine (P > 0.05) and reduction in PONV (P < 0.05) |
Tong et al, 201226 | Randomized, controlled | 90 | Functional endoscopic sinus surgery | Analgesic effect | Reduction of postoperative pain (P < 0.01), decreased dosage of local anesthetic (P < 0.01), increased patient satisfaction scores (P < 0.01) compared to anesthesia alone |
Ochi, 201319 | Retrospective review | 56 | Tonsillectomy | Postoperative pain | Reduction in postoperative pain (P < 0.01) compared to codeine |
Tsao et al, 201513 | Randomized, controlled, double-blind | 59 | Tonsillectomy | Postoperative pain | Reduction in postoperative pain compared to sham acupuncture (P = 0.0065) |
Gilbey et al, 201520 | Randomized, controlled, single-blind | 60 | Tonsillectomy | Pain and unwanted side effects | Reduction in pain with no unwanted side effects (P ≤ 0.01) compared to conventional postoperative analgesic treatment alone |
Shin et al, 201617 | Metaanalysis/systematic review | 800 | Tonsillectomy | PONV | Reduction in PONV (P < 0.05) and lower risk-ratio compared to conventional drug therapy |
Moeen, 201618 | Prospective double-blind | 120 | Tonsillectomy | Postoperative vomiting | Similar antiemetic effects as dexamethasone (P = 0.426) |
Cho et al, 201621 | Metaanalysis/systematic review | 1,025 | Tonsillectomy | PONV and postoperative pain | Reduction in PONV compared to conventional analgesic alone |
Deganello et al, 201623 | Pilot | 48 | Neck dissection | Postoperative pain and dysfunction | Reduction in chronic pain and dysfunction after neck dissection (P < 0.01) compared to physical therapy |
Grech et al, 201624 | Prospective, double-blind pilot | 20 | Thyroid and parathyroid surgery | Analgesic use, pain, physiologic stress, immune cytokine response | Reduction in analgesic use, glycemic levels (P < 0.005), and postoperative stress compared to general anesthesia alone |
PONV, postoperative nausea and vomiting.