Classification and Percent Distribution of Pineal Region Masses in Six Case Seriesa
| World Health Organization Tumor Classification6 | Edwards et al,16 1988 Ages < 18 years n=36 | Regis et al,15 1996 Ages 3-73 years n=370 | Grimoldi et al,18 1998 Ages 9-52 years n=13 | Hernesniemi et al,19 2008 Ages 0-78 yearsb n=101 | Abecassis et al,20 2017 Ages 0-66 years n=51 | Abbassy et al,21 2018 Ages 1-27 years n=11 |
|---|---|---|---|---|---|---|
| Germ cell tumors/Germinomas | 63% / 30% | 34% / 27% | 39% / 31% | 13% / 11% | 38% / 30% | 36% / 18% |
| Pineal parenchymal cell tumors | 12% | 24% | 39% | 32% | 26% | 27% |
| Glial cell tumors | 22% | 34% | 8% | 26% | 14% | 36% |
| Miscellaneous tumors and cysts | 6% | 12% | 15% | 30% | 22% | 0% |
↵aThe papillary tumor of the pineal region classification is not included in this table, as this entity was not defined until 2003 after 3 of the case series were published. We have classified ependymomas and atypical teratoid rhabdoid tumors as glial tumors and papillary tumors of the pineal region as miscellaneous tumors and cysts.
↵bThis series includes 12 vascular lesions that are not included in the table.