Red Flags for Malignancy
| Signs, Symptoms, and Concerns |
|---|
| History of malignancy |
| Strong clinical suspicion |
| Unexplained/unintentional weight loss |
| Age >50 years |
| Failure to improve with 4-6 weeks of treatment |
| Pain at rest |
| Malaise |
| Fever |
| Reduced appetite |
| Rapid fatigue |
| Progressive symptoms |
| Multiple cancer risk factors |
| Paraparesis |
Note: Adapted from Verhagen et al.6