Table 1.

Liver Test Results

Timeline	Total Bilirubin, mg/dL (Reference, 0.2-1.2)	ALT, IU/L (Reference, 17-63)	AST, IU/L (Reference, 15-41)	ALP, IU/L (Reference, 32-91)	Platelet Count, × 10⁹/L (Reference, 150-450)	INR (Reference, <1.0)	Albumin, gm/dL (Reference, 3.5-4.8)
Prior to RAD-140 use, –14 months	1.0	48	26	82	152	–	4.6
Started RAD-140	–	–	–	–	–	–
Routine PCP office visit, +5 weeks	1.2	313	182	103	180	0.8	4.4
Emergency department encounter, +7 weeks	10.8	171	71	151	263	0.85	4.1
Hepatology office visit, +8 weeks	32.3	125	82	181	305	0.96	3.9
Hepatology office visit, +10 weeks	24.8	212	120	251	310	1.47	3.0
Hospital day 1, +10 weeks, 2 days	28.7	155	94	232	341	1.36	2.9
Hospital day 2	26.1	134	76	203	312	1.46	2.5
Hospital day 3	27.3	115	62	199	260	1.61	2.6
Hospital day 4	24.3	117	79	194	268	1.69	2.5
Postdischarge hepatology office visit, +11 weeks	38.5	143	104	189	299	0.84	2.9
Postdischarge hepatology office visit, +14 weeks	24.6	120	118	187	261	0.89	2.9
Postdischarge hepatology office visit, +18 weeks	4.9	118	79	118	170	0.91	4.0

ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate aminotransferase; INR, international normalized ratio; PCP, primary care provider.