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Short- and long-term prognosis of patients with a subarachnoid haemorrhage in relation to intra-operative period of hypotension

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Summary

112 patients operated on for an intracranial aneurysm were surveyed. The immediate (up to 3 days from surgery) and late (from 3 days onwards and up to 2 years) outcome was examined in relation to the level and duration of per-operative hypotension as well as technical difficulties.

The risk of both immediate and late post-operative neurological deficit was increased when the systolic blood pressure was pharmacologically reduced below the level of 60 mm Hg. The duration of such hypotension had a similar influence.

A proportion of patientes, following subarachnoid haemorrhage, respond poorly to hypotension and identificiation of these “vulnerable perfusers” by bedside cerebral blood flow or other monitoring procedures may be useful.

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Hitchcock, E.R., Tsementzis, S.A. & Dow, A.A. Short- and long-term prognosis of patients with a subarachnoid haemorrhage in relation to intra-operative period of hypotension. Acta neurochir 70, 235–242 (1984). https://doi.org/10.1007/BF01406652

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