Original contributionAngiomatoid “malignant fibrous histiocytoma”: An immunohistochemical study indicative of myoid differentiation
References (36)
- et al.
Cytoskeletal properties of alveolar soft part sarcoma
Hum Pathol
(1990) - et al.
Malignant fibrohistiocytic tumors
Angiomatoid malignant fibrous histiocytoma. A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm
Cancer
(1979)- et al.
An ultrastructural study of angiomatoid fibrous histiocytoma
Cancer
(1982) - et al.
Angiomatoid malignant fibrous histiocytoma. Case report and electron microscopic findings
Virchows Arch [A]
(1982) - et al.
Angiomatoid malignant fibrous histiocytoma. Cytology of fine needle aspiration and its differential diagnosis
Arch Pathol Lab Med
(1985) Angiomatoid malignant fibrous histiocytoma. Report of two cases with ultrastructural observations of one case
Arch Pathol Lab Med
(1985)- et al.
Angiomatoid malignant fibrous histiocytoma. Evidence for the histiocytic origin of tumor cells
Virchows Arch [A]
(1985) - et al.
Congenital angiomatoid malignant fibrous histiocytoma. A light-microscopic, immunopathologic and electron-microscopic study
Am J Dermatopathol
(1988) - et al.
Angiomatoid malignant fibrous histiocytoma: Flow cytometric DNA analysis of six cases
J Surg Oncol
(1989)
Angiomatoid malignant fibrous histiocytoma: Cytologic, immunohistochemical, ultrastructural and flow cytometric study of 20 cases
Mod Pathol
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques. A comparison between ABC and unlabelled antibody (PAP) procedures
J Histochem Cytochem
Pigmented neuroectodermal tumour of infancy: An immunohistochemical study
Histopathology
Angiomatoid malignant fibrous histiocytoma: A long term follow up study of 108 cases with evaluation of histologic predictors of outcome
Am J Surg Pathol
Widespread immunoreactivity for alpha-1-antichymotrypsin in different types of tumors
Am J Clin Pathol
Alpha-1-antitrypsin and lysozyme. Their limited significance in fibrohistiocytic tumors
Am J Clin Pathol
The significance of double phenotypic patterns and markers in human sarcomas. A new model of mesenchymal differentiation
Am J Pathol
Malignant fibrous histiocytoma tumor cells resemble fibroblasts
Am J Surg Pathol
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Angiomatoid Fibrous Histiocytoma Mimicking Eosinophilic Granuloma in a Pediatric Patient
2019, World NeurosurgeryCitation Excerpt :In pathology, AFH is characterized by nodular tumor cells, pseudoangiomatoid spaces, fibrous pseudomembranes, and the lymphocyte infiltration.1,9 There are no sensitive and specific immunohistochemical antibodies that have been found except vimentin that showed diffuse positive in all reported cases at present, whereas the presence of EWSR1-CREB1 fusion gene can assist in the diagnosis of AFH.1,10-14 AFH appears as a painless soft tissue mass in the subcutaneous or deep dermal layer of the body, and is often confused with malignant fibrous histiocytoma on MRI if occurring in soft tissues.15,16
Mesenchymal Tumors with EWSR1 Gene Rearrangements
2019, Surgical Pathology ClinicsCitation Excerpt :Angiomatoid fibrous histiocytoma (originally described as angiomatoid malignant fibrous histiocytoma)157 is a soft tissue tumor of intermediate biologic potential. AFH typically arises within extremity deep dermis and subcutis in children and young adults,157–159 but can arise in older adults and in a variety of sites, including the head and neck and trunk, and more rarely other soft tissue sites or in viscera,14,160–168 and is sometimes associated with systemic symptoms.169 Most AFHs behave in a relatively indolent manner, although local recurrence occurs in up to 15%.
Spindle Cell Tumors: Common Clinical Associations
2019, Practical Soft Tissue Pathology: A Diagnostic Approach A Volume in the Pattern Recognition SeriesTumors Often Associated With Prominent Lymphocytes and/or Plasma Cells
2019, Practical Soft Tissue Pathology: A Diagnostic Approach A Volume in the Pattern Recognition SeriesAngiomatoid fibrous histiocytoma of the radial pulse groove
2018, Annales de Dermatologie et de VenereologieFibrohistiocytic Tumors
2017, Clinics in Laboratory MedicineCitation Excerpt :The mitotic rate is generally low, but occasional cases show marked nuclear pleomorphism, a finding of uncertain clinical significance.72,80 Angiomatoid fibrous histiocytoma shows an unusual and unique immunophenotype, expressing the triad of desmin, EMA, and CD68 in approximately one-half of cases (Fig. 15E–G).73,81 Although not diagnostically significant, it is important to recognize that angiomatoid fibrous histiocytoma may express CD99.
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Dr Fletcher is supported by and is a Senior Clinical Research Fellow with the Cancer Research Campaign (United Kingdom).