EpidemiologyRelation of body weight to development of ischemic heart disease in a cohort of young north American men after a 26 year observation period: The manitoba study*
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2017, Diabetes and Metabolic Syndrome: Clinical Research and ReviewsCitation Excerpt :As expected, we observed a gradual increase of the documented 10-year CVD incidence according to the baseline BMI class in both genders, Importantly, BMI, waist circumference, WHR, WHtR and WHHR were independently associated with the 10-year CVD incidence even in multivariate models including other known CVD risk factors. These findings are in accord with the reported results from previous cohorts, showing an independent association between baseline BMI and long-term CVD incidence [14]. In the Framingham cohort study, which followed patients aged 28–62 years for a mean of 26 years, the group with increased body weight had higher coronary heart disease (CHD) risk compared with the leanest group, independently of age, cholesterol, systolic blood pressure, smoking, left ventricular hypertrophy and glucose intolerance [15].
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This study was supported by The Department of National Health and Welfare and The Defence Research Board, Ottawa, Ontario, Canada.