Original articleEndogenous Fungal Endophthalmitis: Causative Organisms, Management Strategies, and Visual Acuity Outcomes
Section snippets
Methods
Microbiologic and clinical records were reviewed from all patients treated at Bascom Palmer Eye Institute (BPEI) between January 1, 1990, and July 1, 2009, for intraocular culture-proven endogenous fungal endophthalmitis (n = 51). After obtaining a list of the causative organisms, the corresponding medical records were reviewed for clinical presentation, treatment strategy, and outcomes. Study inclusion criteria were positive fungal culture results and clinical course consistent with endogenous
Demographics
Study criteria were met in 51 patients (65 eyes). Of the 51 patients included in this study, 30 were men. The mean age was 51 years, with a range from 3 months to 92 years. Three patients were younger than 1 year of age. Follow-up ranged from 2 days to more than 15 years (median, 138 days). Fourteen patients had bilateral endogenous fungal endophthalmitis.
Time from onset of symptoms to presentation ranged from 0 to 60 days (mean, 13 days). No patients were identified through routine screening.
Discussion
The clinical features and presentation of endogenous fungal endophthalmitis have been reported previously in multiple case reports and small clinical case series.1, 2, 3, 10, 11, 12 Few reviews have focused solely on endogenous fungal endophthalmitis. In addition, not all previously reported cases have been both microbiologically and clinically confirmed. To our knowledge, this study is the largest series of culture-proven endogenous fungal endophthalmitis.
Retinal detachment is not an uncommon
Ahila Lingappan, MD, received her medical degree from Baylor College of Medicine in Houston, Texas. In 2010, she completed her ophthalmology residency at the Bascom Palmer Eye Institute in Miami, Florida. She is currently practicing general ophthalmology in Voorhees, New Jersey.
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Ahila Lingappan, MD, received her medical degree from Baylor College of Medicine in Houston, Texas. In 2010, she completed her ophthalmology residency at the Bascom Palmer Eye Institute in Miami, Florida. She is currently practicing general ophthalmology in Voorhees, New Jersey.