Coronary artery diseaseImpact of Multivessel Coronary Artery Disease and Noninfarct-Related Artery Revascularization on Outcome of Patients With ST-Elevation Myocardial Infarction Transferred for Primary Percutaneous Coronary Intervention (from the EUROTRANSFER Registry)
Section snippets
Methods
A detailed description of the EUROTRANSFER Registry (http://ClinicalTrials.gov, number NCT00378391) protocol and main results have been previously published.19, 20 In this registry data concerning 1,650 consecutive, transferred patients with STEMI in 15 STEMI hospital networks from 7 European countries from November 2005 to January 2007 were collected. For the present analysis data of 1,598 patients with complete angiographic data, with ≥1 significantly stenosed epicardial coronary artery, and
Results
Data on 1,598 patients were retrieved from the EUROTRANSFER Registry database. Patients with 1-, 2-, and 3-vessel disease made up 48.5%, 32.0%, and 19.5% of the registry population, respectively. As presented in Table 1, patients with MVD were older, with a higher prevalence of diabetes mellitus, previous MI, previous heart failure symptoms, previous PCI, and presenting in a higher Killip class on admission than were patients with 1-vessel disease. There was no difference in initial
Discussion
In this study we confirmed findings from previous reports concerning an unfavorable prognosis of patients with MVD presenting with STEMI.1, 2, 3 Prevalence of MVD in the EUROTRANSFER Registry was similar to the prevalence observed in previous reports1, 2, 3, 4, 5 and MVD was associated with a higher prevalence of diabetes mellitus, previous chronic heart failure symptoms, and advanced age.2, 3, 21 In addition, in patients with MVD, a trend toward higher frequency of chronic renal failure and
References (24)
- et al.
Outcome of urgent percutaneous transluminal coronary angioplasty in acute myocardial infarction: comparison of single-vessel versus multivessel coronary artery disease
Am Heart J
(1992) - et al.
Results of primary angioplasty in patients with multivessel disease
Rev Esp Cardiol
(1998) - et al.
Multivessel percutaneous coronary intervention in Chinese patients with acute myocardial infarction and simple nonculprit arteries
Am J Med Sci
(2007) - et al.
Exaggeration of nonculprit stenosis severity during acute myocardial infarction: implications for immediate multivessel revascularization
J Am Coll Cardiol
(2002) - et al.
Impact of multivessel coronary disease on long-term mortality in patients with ST-elevation myocardial infarction is due to the presence of a chronic total occlusion
Am J Cardiol
(2006) - et al.
Culprit only versus complete coronary revascularization during primary PCI
Int J Cardiol
(2008) - et al.
Prevalence, predictors, and in-hospital outcomes of non-infarct artery intervention during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (from the National Cardiovascular Data Registry)
Am J Cardiol
(2009) - et al.
Multivessel percutaneous coronary intervention in patients with multivessel disease and acute myocardial infarction
Am Heart J
(2004) - et al.
Initial experience with multivessel percutaneous coronary intervention during mechanical reperfusion for acute myocardial infarction
Am J Cardiol
(2001) - et al.
European registry on patients with ST-elevation myocardial infarction transferred for mechanical reperfusion with a special focus on early administration of abciximab—EUROTRANSFER Registry
Am Heart J
(2008)
Early abciximab administration before transfer for primary percutaneous coronary interventions for ST-elevation myocardial infarction reduces 1-year mortality in patients with high-risk profileResults from EUROTRANSFER registry
Am Heart J
Multivessel coronary artery disease: a key predictor of short-term prognosis after reperfusion therapy for acute myocardial infarctionThrombolysis and Angioplasty in Myocardial Infarction (TAMI) Study Group
Am Heart J
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The EUROTRANSFER Registry was an academic research project supported by a research grant from Eli Lilly and Company, Critical Care Europe, Geneva, Switzerland.