Health Policy & EconomicsProjected Economic Burden of Periprosthetic Joint Infection of the Hip and Knee in the United States
Section snippets
Methods
We used the Nationwide Inpatient Sample (NIS) to determine the number of primary and revision knee and hip arthroplasties performed between January 1, 2002 and December 31, 2017. The NIS is a publicly available all-payer database containing data on over 7 million hospital visits. The database is designed for the calculation of both national and regional estimates of clinical diagnoses and inpatient procedures [11]. The NIS was created with the intention to inform healthcare policy.
Within the
Results
The annual number of infected THAs increased from 5075 in 2002 to 8635 in 2012 (Table 1, Fig. 1). Over the next 5-year period, the annual number of infected THAs increased to 11,985 in 2017. In 2002, the number of infected TKAs was 8,205, increasing to 17,055 in 2012. By 2017, the estimated annual number of infected TKAs increased to 28,161.
Although average cost per case of THA or TKA PJI remained relatively stable over the period from 2002 to 2017, total costs nationally increased drastically
Discussion
PJI of the hip and knee remains a significant burden to the US healthcare system. Utilizing the most recent high-quality national data, we have projected PJI growth and its associated economic burden through 2030. The combined estimated annual hospital costs of PJI for the hip and knee were estimated to be $1.85 billion by 2030. This estimate includes $753.4 million for THA PJI and $1.1 billion for TKA PJI, in that year.
Prior estimates of the cost of PJI in the United States were generally
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Ajay Premkumar and David A. Kolin contributed equally to this manuscript.
One or more of the authors of this paper have disclosed potential or pertinent conflicts of interest, which may include receipt of payment, either direct or indirect, institutional support, or association with an entity in the biomedical field which may be perceived to have potential conflict of interest with this work. For full disclosure statements refer to https://doi.org/10.1016/j.arth.2020.12.005.