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Primary squamous cell carcinoma of the thyroid

https://doi.org/10.1053/ejso.2001.1180Get rights and content

Abstract

Aims: To investigate the clinical features and treatment protocol of squamous cell carcinoma of the thyroid (SCCT). Method: Clinical records of four SCCT patients treated during 1985–99 were retrospectively reviewed and evaluated. Results: Two patients who underwent surgical excision plus radiotherapy died of local tumour recurrence, 6 and 13 months, respectively, post-operatively. One who accepted surgery only died 4 months later of respiratory distress. The fourth patient who had radical surgery coupled with radiotherapy and chemotherapy was disease-free at 26-month follow-up. Conclusion: SCCT is a very rare but highly malignant carcinoma. Early diagnosis and an aggressive radical surgery portend a better prognosis. Radiotherapy and chemotherapy are secondary applicable methods for the patients with certain condition.

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    When only incomplete resection is achievable, radical or palliative radiotherapy following the surgery is widely used and is recognized as an essential modality for obtaining locoregional control in cases of thyroid cancer. Although the main treatment for SCC of the thyroid is surgery followed by radiotherapy or concurrent chemoradiotherapy, most reported cases were found to be unresponsive [17]. On the other hand, Cook et al. reported the largest review of primary SCCs of the thyroid.

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Correspondence to: Department of Head and Neck Surgery, Chongqing Cancer Hospital, Han Yu Road, Chongqing, 400030, China. Fax: +86-23-65316087; E-mail: [email protected]

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