Imaging and Diagnostic TestingReproducibility of exaggerated blood pressure response to exercise in healthy patients☆
Section snippets
Study population
We conducted an observational, retrospective study.
The Israeli Defense Force maintains a periodical examination center for its personnel. Patients undergo medical check-ups at 3-year intervals. Aside from the stress testing, each examination includes a medical interview, physical examination, electrocardiography, and blood sampling for fasting glucose level and lipid profile. Stress test ergometry was performed in all patients >39 years of age and/or having ≥2 risk factors for cardiovascular
Baseline characteristics
When comparing the patients’ data between the groups at the time the first ExBPR occurred, the concordant group showed no characteristic feature (Table I).Parameter Concordant group (n = 18) Discordant group (n = 99) Control group (n = 81) Age (y) 36.5 ± 2.8 36.8 ± 4.2 35 ± 4.1 BMI (kg/m2) 25.5 ± 2.8 24.6 ± 2.9 24.2 ± 2.7 Fasting glucose (mg/dL) 98.4 ± 23.5 88.9 ± 15.7 89.7 ± 16.7 Cholesterol (mg/dL) 209 ± 33.7 208.2 ± 39.4 192.2 ± 43*
Discussion
Our study shows that for most of the patients with ExBPR, the high blood pressure measurements during stress are not reproducible. The change in SBP from rest to exercise also showed little reproducibility in the ExBPR responders. Those with consistent ExBPR are a relatively small number of patients who could not be distinguished by any clinically significant parameter, although SBP at rest and after 3 minutes of recovery was higher in both study groups than in the control group. Our findings,
References (18)
- et al.
Follow-up of normotensive men with exaggerated blood pressure response to exercise
Am Heart J
(1983) - et al.
Blood pressure at rest and during maximal dynamic and isometric exercise as predictors of systemic hypertension
Am J Cardiol
(1988) - et al.
End-organ disease in hypertension: what have we learned?
J Cardiovasc Pharmacol
(1992) - et al.
Left ventricular mass in diabetes-hypertension
Arch Intern Med
(1992) - et al.
Are the clinical and hemodynamic events during exercise stress testing in invasive studies in patients with angina pectoris reproducible?
Circulation
(1980) - et al.
Relationship between blood pressure response during exercise and tendency to left ventricular hypertrophy
Jpn Circ J
(1990) - et al.
Left ventricular hypertrophy in hypertension: correlation with rest, exercise and ambulatory systolic blood pressure
J Hypertens
(1986) - et al.
Blood pressure response during treadmill testing as a risk factor for new-onset hypertension: the Framingham Heart Study
Circulation
(1999) - et al.
Left ventricular hypertrophy in men with normal blood pressure: relation to exaggerated blood pressure response to exercise
Ann Intern Med
(1990)
Cited by (15)
Hypertensive Response With Exercise to Reveal Increased Cardiovascular Risk in Adults With Aortic Coarctation Repair: Value and Caution
2018, Canadian Journal of CardiologyImpact of exaggerated blood pressure response in normotensive individuals on future hypertension and prognosis: Systematic review according to PRISMA guideline
2017, Advances in Medical SciencesCitation Excerpt :Interestingly, studies found on the one hand that BP during exercise was strongly associated with BP values at rest, and patients with EBPR had significantly higher BP values at rest [90]. On the other hand, EBPR in CPET were rarely reproducible [91]. These findings seem to be conflicting.
Blood pressure response to exercise testing
2010, Apunts Medicina de l'EsportPrognostic Value of an Exaggerated Exercise Blood Pressure Response in Patients With Diabetes Mellitus and Known or Suspected Coronary Artery Disease
2010, American Journal of CardiologyCitation Excerpt :Only a small proportion of the patients included in the present study underwent coronary angiography; thus, the association of an EESBPR with the angiographic findings could not be properly assessed. In addition, the reproducibility of an EESBPR has been reported to be low.26 Almost all patients included in our study were white; hence, we could not assess any racial heterogeneity in our cohort.
Exercise-induced arterial hypertension: possible predictor of cardiovascular risk
2009, Hipertension y Riesgo VascularExercise Blood Pressure Response, Albuminuria, and Arterial Stiffness in Patients with Hypertension
2009, American Journal of Medicine
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Reprint requests: Dr Yehonatan Sharabi, Internal Medicine D, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel. E-mail: [email protected]