Acute cholestatic hepatitis by cytomegalovirus in an immunocompetent patient resolved with ganciclovir

C Serna-Higuera; M González-García; J M Milicua; V Muñoz

doi:10.1097/00004836-199910000-00010

Acute cholestatic hepatitis by cytomegalovirus in an immunocompetent patient resolved with ganciclovir

J Clin Gastroenterol. 1999 Oct;29(3):276-7. doi: 10.1097/00004836-199910000-00010.

Authors

C Serna-Higuera¹, M González-García, J M Milicua, V Muñoz

Affiliation

¹ Department of Gastroenterology, Ramón y Cajal Hospital, Faculty of Medicine, Alcalá de Henares University, Madrid, Spain.

PMID: 10509956
DOI: 10.1097/00004836-199910000-00010

Abstract

We report a case of acute cholestatic hepatitis in an immunocompetent young male with cytomegalovirus (CMV) primoinfection episode. The severity of the clinical symptoms led to a high-dose treatment with parenteral ganciclovir, with an immediate response and total resolution of symptoms. Therapeutic options are discussed, particularly the use of ganciclovir, even in immunocompetent patients when the severity of the symptoms could demand it.

Publication types

Case Reports

MeSH terms

Acute Disease
Adult
Antiviral Agents / administration & dosage*
Cholestasis, Intrahepatic / diagnosis
Cholestasis, Intrahepatic / drug therapy*
Cholestasis, Intrahepatic / immunology
Cytomegalovirus Infections / diagnosis
Cytomegalovirus Infections / drug therapy*
Cytomegalovirus Infections / immunology
Disease-Free Survival
Ganciclovir / administration & dosage*
Hepatitis, Viral, Human / diagnosis
Hepatitis, Viral, Human / drug therapy*
Hepatitis, Viral, Human / immunology
Humans
Immunocompetence*
Male
Treatment Outcome

Substances

Antiviral Agents
Ganciclovir