Innovative medical management with resection for successful treatment of pulmonary mucormycosis despite diagnostic delay

Karen M MacKenzie; Katherine L Baumgarten; Boyd M Helm; P Michael McFadden; Nicholas J Deduska; George E Loss Jr; James D Eason

Innovative medical management with resection for successful treatment of pulmonary mucormycosis despite diagnostic delay

J La State Med Soc. 2002 Mar-Apr;154(2):82-5.

Authors

Karen M MacKenzie¹, Katherine L Baumgarten, Boyd M Helm, P Michael McFadden, Nicholas J Deduska, George E Loss Jr, James D Eason

Affiliation

¹ Surgery Department, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.

PMID: 12014459

Abstract

We present a case of primary pulmonary mucormycosis infection in a renal transplant recipient diagnosed serendipitously by computed tomography scan. Treatment included discontinuation of immunosuppressive regimen, initiation of antifungal therapy with amphotericin B lipid complex, administration of granulocyte-macrophage colony stimulating factor, surgical excision of the involved lobe, and outpatient treatment with amphotericin B with dialysis. The patient ultimately required transplant nephrectomy as a result of immunosuppression discontinuation.

Publication types

Case Reports

MeSH terms

Amphotericin B / therapeutic use*
Antifungal Agents / therapeutic use*
Female
Granulocyte-Macrophage Colony-Stimulating Factor / therapeutic use
Humans
Immunosuppressive Agents
Kidney Transplantation
Lung Diseases, Fungal / complications
Lung Diseases, Fungal / diagnostic imaging
Lung Diseases, Fungal / therapy*
Middle Aged
Mucormycosis / complications
Mucormycosis / diagnostic imaging
Mucormycosis / therapy*
Pneumonectomy*
Radiography

Substances

Antifungal Agents
Immunosuppressive Agents
Amphotericin B
Granulocyte-Macrophage Colony-Stimulating Factor