Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1

M J Naidich; M T Walker; N R Gottardi-Littell; G Han; J P Chandler

doi:10.1007/s00234-004-1216-0

Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1

Neuroradiology. 2004 Oct;46(10):825-9. doi: 10.1007/s00234-004-1216-0.

Authors

M J Naidich¹, M T Walker, N R Gottardi-Littell, G Han, J P Chandler

Affiliation

¹ Department of Radiology, Northwestern Memorial Hospital and Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. m-naidich@northwestern.edu

PMID: 15289955
DOI: 10.1007/s00234-004-1216-0

Abstract

We describe a case of cerebellar pleomorphic xanthoastrocytoma (PXA) occurring in a patient with neurofibromatosis type 1 (NF1). The histomorphology of this uncommon glial (astrocytic) neoplasm is discussed. The occurrence of this tumor within the posterior fossa is extremely rare. To our knowledge, this is the first reported case of a cerebellar PXA in a patient with NF1.

Publication types

Case Reports

MeSH terms

Astrocytoma / pathology*
Astrocytoma / surgery
Cerebellar Neoplasms / pathology*
Cerebellar Neoplasms / surgery
Female
Humans
Middle Aged
Neurofibromatosis 1 / pathology*
Neurofibromatosis 1 / surgery