Pain on injection and venous sequelae following two formulations of etomidate

Eur J Anaesthesiol. 1989 Nov;6(6):431-4.

Abstract

In forty patients (aged 21-76 years) scheduled for elective surgery, anaesthesia was induced with either etomidate in propylene glycol (n = 20) or etomidate in ethanol (n = 20) injected via a 23-G needle over 30 s. The overall incidence of pain on injection was 60%. No statistically significant difference was found between the two groups. The incidence of venous sequelae was 5%, in both groups.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anesthesia, Intravenous / adverse effects*
  • Ethanol / administration & dosage
  • Etomidate / administration & dosage*
  • Female
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pain / etiology*
  • Propylene Glycol
  • Propylene Glycols / administration & dosage
  • Randomized Controlled Trials as Topic
  • Thrombophlebitis / chemically induced*

Substances

  • Propylene Glycols
  • Ethanol
  • Propylene Glycol
  • Etomidate