Abstract
Two fatal cases of rhinocerebral mucormycosis with fungal invasion and occlusion of the internal carotid artery are described. Review of the literature reveals 35 similar cases of whom only 6 survived. Emphasis is placed on the need for early diagnosis and prompt therapy which consists of correction of the underlying disease, aggressive surgical debridement, and amphotericin B.
MeSH terms
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Adolescent
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Adult
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Aged
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Amphotericin B / therapeutic use
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Brain Diseases / diagnosis*
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Brain Diseases / drug therapy
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Brain Diseases / surgery
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Carotid Artery Diseases / diagnosis*
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Carotid Artery Diseases / drug therapy
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Carotid Artery Diseases / surgery
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Child
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Child, Preschool
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Debridement
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Female
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Humans
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Infant
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Male
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Middle Aged
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Mucormycosis / diagnosis*
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Mucormycosis / drug therapy
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Mucormycosis / surgery
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Nose Diseases / diagnosis*
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Nose Diseases / drug therapy
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Nose Diseases / surgery
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Orbital Diseases / diagnosis
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Orbital Diseases / drug therapy
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Orbital Diseases / surgery
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Paranasal Sinus Diseases / diagnosis
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Paranasal Sinus Diseases / drug therapy
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Paranasal Sinus Diseases / surgery