Severe community-acquired pneumonia: factors influencing need of intensive care treatment and prognosis

Scand J Infect Dis. 1985;17(4):377-86. doi: 10.3109/13813458509058778.

Abstract

53 patients with community-acquired pneumonia requiring treatment in an Intensive Care Unit (ICU) were studied retrospectively. The majority of patients (77%) had some predisposing factor: illness, smoking or alcoholism. A cause of pneumonia was established in 53% of the cases; Streptococcus pneumoniae was the dominating pathogen. Immediate active treatment was required in 70% of the patients and 58% were treated with mechanical ventilation. The overall mortality was 25% (32% among patients treated with mechanical ventilation) and rose to 39% when a follow-up period of 3.25 years on average was included. A significantly higher mortality rate was seen among elderly patients and among those who were previously immunocompromised or who had a leukocyte count of less than or equal to 9 X 10(9)/l on admission to hospital. It is concluded that although the mortality rate was considerable among the 53 ICU-treated patients with severe community-acquired pneumonias, several were saved by intensive care treatment. Most of those who survived their pneumonia eventually recovered fully.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Barotrauma / etiology
  • Blood Cell Count
  • Blood Sedimentation
  • Cross Infection / etiology
  • Dexamethasone / administration & dosage
  • Female
  • Follow-Up Studies
  • Humans
  • Immune Tolerance
  • Injections, Intravenous
  • Intensive Care Units
  • Length of Stay
  • Lung Injury
  • Male
  • Mediastinal Emphysema / etiology
  • Methylprednisolone / administration & dosage
  • Middle Aged
  • Pneumonia / complications
  • Pneumonia / drug therapy
  • Pneumonia / mortality
  • Pneumonia / transmission*
  • Pneumothorax / etiology
  • Prognosis
  • Pulmonary Embolism / etiology
  • Retrospective Studies
  • Smoking

Substances

  • Anti-Bacterial Agents
  • Dexamethasone
  • Methylprednisolone