Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss

M A Alpert; C R Lambert; H Panayiotou; B E Terry; M V Cohen; C V Massey; M W Hashimi; V Mukerji

doi:10.1016/s0002-9149(99)80338-5

Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss

Am J Cardiol. 1995 Dec 1;76(16):1194-7. doi: 10.1016/s0002-9149(99)80338-5.

Authors

M A Alpert¹, C R Lambert, H Panayiotou, B E Terry, M V Cohen, C V Massey, M W Hashimi, V Mukerji

Affiliation

¹ Division of Cardiology, University of South Alabama College of Medicine, Mobile, Alabama 36617, USA.

PMID: 7484912
DOI: 10.1016/s0002-9149(99)80338-5

Abstract

Longer duration of morbid obesity is associated with higher LV mass, poorer LV systolic function, and greater impairment of LV diastolic filling. Weight loss-induced decreases in LV mass and improvements in LV systolic function and diastolic filling are due in part to favorable alterations in LV loading conditions.

MeSH terms

Adult
Blood Pressure
Diastole
Echocardiography
Female
Heart Ventricles / pathology
Heart Ventricles / physiopathology
Humans
Male
Myocardial Contraction
Obesity, Morbid / pathology
Obesity, Morbid / physiopathology*
Time Factors
Ventricular Function, Left*
Weight Loss*