Denosumab, a human monoclonal antibody to the receptor activator of nuclear factor-κB
ligand, is a novel therapy to osteoporotic fracture and skeletal-related events in patients with …

Aims We conducted a systematic review and meta-analysis on three outcomes. We
assessed the efficacy and safety of direct oral anticoagulants (DOAC) compared to vitamin K …

Background Acute pulmonary embolism (APE) is a potentially fatal disease with high mortality.
Prior studies have shown an increased frequency of central localization of the clot, right …

We report an atypical case of Clostridium difficile (C. difficile) infection in a 35-year male who
presented to the hospital because of diffuse abdominal pain associated with nausea and …

Acute monoarthritis is one of the most common rheumatologic presentations. However, it is
clinically difficult to distinguish between an inflamed joint due to crystal-induced arthritis and …

We report a case of autoimmune necrotizing myopathy related to statin use in a 70-year-old
woman who came to the hospital because of progressive lower extremity weakness. …

More than 90 % of cases of pneumocystis pneumonia (PCP) in adults occur in patients with
chronic HIV infection with CD4 counts lower than 200 cells/ml. Even though primary HIV …

A 34-year-old man with no significant medical history presented to the emergency room (ER)
after an episode of thunderclap headache. His symptoms began with dry heaves but no …

A 43-year-old white woman presented to the emergency department with confusion, agitation,
and progressive dyspnea. Chest x-ray revealed pulmonary edema. Initial diagnostic …

… 3 , Edward Bischof …