User profiles for Thomas J Santoro

Thomas J. Santoro

Chief Medical Officer
Verified email at innovhs.com
Cited by 1794

The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice.

TJ Santoro, JP Portanova, BL Kotzin - The Journal of experimental …, 1988 - rupress.org
The current study examines the role of the L3T4 T cell subset in the development of lupus-like
autoimmunity and lymphoproliferation in lpr-bearing mice. Chronic treatment of MRL-lpr/…

[HTML][HTML] Hypoxia driven opioid targeted automated device for overdose rescue

MS Imtiaz, CV Bandoian, TJ Santoro - Scientific Reports, 2021 - nature.com
Opioid use disorder has been designated a worsening epidemic with over 100,000 deaths
due to opioid overdoses recorded in 2021 alone. Unintentional deaths due to opioid …

Studies of congenic MRL-Ipr/Ipr. xid mice.

EB Steinberg, TJ Santoro, TM Chused… - … (Baltimore, Md.: 1950 …, 1983 - journals.aai.org
Highly inbred MRL-Ipr/Ipr.xid congenic mice were bred and compared with their + littermates.
The xid-bearing congenics developed lymphadenopathy consisting of dull Ly-1+ T cells …

Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice

TJ Santoro, JL Bryant, J Pellicoro, ME Klotman… - Virology, 1994 - Elsevier
The mechanisms which predispose to growth failure in infants and children infected with
immunodeficiency virus type-1 (HIV-1) are not fully understood. The contributions of viral …

Anatomical distribution of small cell lung cancer: effects of lobe and gender on brain metastasis and survival

AE Sahmoun, LD Case, TJ Santoro… - Anticancer …, 2005 - ar.iiarjournals.org
Background: Primary small cell lung cancer (SCLC) has a predilection for the right rather
than the left lung. The aim of this study was to examine the association between gender and …

The potential pathogenetic link between peripheral immune activation and the central innate immune response in neuropsychiatric systemic lupus erythematosus

M Tomita, RL Khan, BH Blehm, TJ Santoro - Medical hypotheses, 2004 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology.
Neuropsychiatric disturbances unexplained by drugs or by other untoward manifestations of …

[HTML][HTML] Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription

…, BJ Holman, CP Santoro, TJ Santoro - Journal of …, 2005 - Springer
Background In neuropathological processes associated with neutrophilic infiltrates, such as
experimental allergic encephalitis and traumatic injury of the brain, the CXC chemokine, …

Tea pigments inhibit the production of type 1 (TH1) and type 2 (TH2) helper T cell cytokines in CD4+ T cells

M Tomita, KI Irwin, ZJ Xie, TJ Santoro - Phytotherapy Research, 2002 - Wiley Online Library
Tea pigments are oxidized products of polyphenols derived from tea leaves (Camellia
sinensis). Theaflavins are constituents of tea pigments with antioxidant, antineoplastic and …

Cerebellar dysfunction is associated with overexpression of proinflammatory cytokine genes in lupus

…, LS Williams, KCH Pang, TJ Santoro - Journal of …, 2001 - Wiley Online Library
Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology
accompanied by central nervous system involvement in up to 60% of patients. The current study …

Aberrant cytokine gene expression in the hippocampus in murine systemic lupus erythematosus

M Tomita, BJ Holman, TJ Santoro - Neuroscience letters, 2001 - Elsevier
Cytokines are important mediators of immune regulation and have been implicated in the
pathogenesis of the neurological disturbances, which occur in up to sixty percent of patients …