Therapeutic strategies for the treatment of sickle cell disease

MK Safo, A Aljahdali, J Burnett… - … chemistry and drug …, 2003 - Wiley Online Library
There are many important new advances in the development of clinically viable therapeutic
options to mitigate the pathophysiology of sickle cell disease (SCD). Some of the most …

[HTML][HTML] NK Cells in Myeloproliferative Neoplasms (MPN)

E Naismith, J Steichen, S Sopper, D Wolf - Cancers, 2021 - mdpi.com
Simple Summary NK cells are important innate immune effectors that contribute substantially
to tumor control, however the role of NK cells in haematological cancers is not as well …

[HTML][HTML] Identification of therapeutic targets for inflammation in sickle cell disease (SCD) among Indian patients using gene expression data analysis

I Das, H Mishra, PK Khodiar, PK Patra - Bioinformation, 2018 - ncbi.nlm.nih.gov
Sickle cell disease (SCD) is life-threatening hemoglobinopathy prevalent in India, Sub-
Saharan Africa and Middle East. Inflammation plays a pivotal role in disease process and …

A Scientific Renaissance: Novel Drugs in Sickle Cell Disease

AU Zaidi, MM Heeney - Pediatric Clinics, 2018 - pediatric.theclinics.com
It has been 2 decades since hydroxyurea was approved by the US Food and Drug
Administration (FDA) for the treatment of sickle cell disease (SCD) in adults, and until …

Mycobacterium avium complex presenting as pulmonary nodules in a child with sickle cell disease

TA Pham, LT Samuel, C Lefevre… - Journal of Pediatric …, 2019 - journals.lww.com
The case of a 10-year-old child with sickle cell disease with pulmonary nodules and
prolonged fevers is reported here. The child was first diagnosed with sarcoidosis based on …

[PDF][PDF] Treatment Options for Complications of Sickle-cell Disease in Children

CED Dassy, MI Saramba, D Zhao - International Journal of Medical …, 2020 - mdpub.net
Prospecting clinical, comprehensive and approach paradigms of therapeutic management
in pediatric age groups with the sickle-cell disease is the mainstay indigence. Data over the …