Drug development research in pregnant and lactating women
Z Ren, AA Bremer, AC Pawlyk - American journal of obstetrics and …, 2021 - Elsevier
Pregnant and lactating women are considered “therapeutic orphans” because they
generally have been excluded from clinical drug research and the drug development …
generally have been excluded from clinical drug research and the drug development …
A life-course approach to tackling noncommunicable diseases in women
Women's health has been critically underserved by a failure to look beyond women's sexual
and reproductive systems to adequately consider their broader health needs. In almost …
and reproductive systems to adequately consider their broader health needs. In almost …
Sex is a defining feature of neuroimaging phenotypes in major brain disorders
Sex is a biological variable that contributes to individual variability in brain structure and
behavior. Neuroimaging studies of population‐based samples have identified normative …
behavior. Neuroimaging studies of population‐based samples have identified normative …
[HTML][HTML] Comprehensive overview of vaccination during pregnancy in Europe
Vaccinations during pregnancy can protect the mother from several infections, thus blocking
vertical transmission. Furthermore, through passive antibody transfer, the newborn can be …
vertical transmission. Furthermore, through passive antibody transfer, the newborn can be …
Pharmacokinetic Evaluation in Pregnancy—Current Status and Future Considerations: Workshop Summary
D Guinn, L Sahin, EP Fletcher, SY Choi… - The Journal of …, 2023 - Wiley Online Library
As pregnant individuals have traditionally been excluded from clinical trials, there is a gap in
knowledge at the time of drug approval regarding safety, efficacy, and appropriate dosing for …
knowledge at the time of drug approval regarding safety, efficacy, and appropriate dosing for …
[HTML][HTML] Influence of Liposomes' and Lipoplexes' Physicochemical Characteristics on Their Uptake Rate and Mechanisms by the Placenta
L Fliedel, K Alhareth, J Seguin, M El-Khashab… - International Journal of …, 2022 - mdpi.com
Pregnant women are still considered as drug orphans. Developing new medications for
pregnancy complications is an urgent need. Nanomedicines seem to be a promising …
pregnancy complications is an urgent need. Nanomedicines seem to be a promising …
[HTML][HTML] Safety of drugs and CAM products in pregnancy and breastfeeding: evidence from clinical toxicology
Perinatal medicine and pharmacology focus on the wellbeing and health of women and
newborns throughout all stages of pregnancy, from conception to birth, and in the first year of …
newborns throughout all stages of pregnancy, from conception to birth, and in the first year of …
Improving Racial and Ethnic Equity in Clinical Trials Enrolling Pregnant and Lactating Individuals
AF Louis‐Jacques, AJ Heuberger… - The Journal of …, 2023 - Wiley Online Library
Racial and ethnic marginalized populations have historically been poorly represented,
underrecruited, and underprioritized across clinical trials enrolling pregnant and lactating …
underrecruited, and underprioritized across clinical trials enrolling pregnant and lactating …
Haematological changes from conception to childbirth: An indicator of major pregnancy complications
Background About 800 women die every day worldwide from pregnancy‐related
complications, including excessive blood loss, infections and high‐blood pressure (World …
complications, including excessive blood loss, infections and high‐blood pressure (World …
Lower Extremity Considerations in the Pregnant Patient
AT Black, S Yancovitz, A Rouse… - Foot & Ankle …, 2023 - journals.sagepub.com
There remains a paucity of literature on musculoskeletal dysfunction, biomechanics, and
pathologies of the lower extremity during pregnancy. There are a multitude of physiologic …
pathologies of the lower extremity during pregnancy. There are a multitude of physiologic …